2-FMA | Analytical Grade Fluorinated Methamphetamine for Research
Product Overview
2-FMA research amphetamine (2-Fluoromethamphetamine) is a synthetic ring-substituted fluorinated analog of methamphetamine and a prominent member of the phenethylamine class. According to the 2-FMA Wiki, it features a fluorine atom substituted at the ortho– ($2$-) position of the phenyl ring, paired with an $N$-methyl modification on the amino group. This specific halogenated configuration makes 2-FMA a primary subject of interest for investigators examining monoamine transporter dynamics, structural-activity relationships (SAR) of methylated phenethylamines, and the metabolic impact of strong carbon-fluorine bonds. It serves as a vital comparative reference standard alongside other fluorinated isomers like 3-FMA and 4-FMA.
2-FMA research amphetamine
Researchers can source high-purity reagents and reference materials directly through Chem S Supply.
Technical Specifications
| Parameter | Specification |
| Chemical Name | 1-(2-fluorophenyl)-N-methylpropan-2-amine |
| Class | Fluorinated Methamphetamine / Phenethylamine |
| Concentration | Available as highly purified crystalline powder or hydrochloride (HCl) salt calibrated for quantitative analysis |
| Format | Analytical grade powder optimized for high stability, precise mass measurement, and solution preparation |
| Purity | $\ge 98\%$ verified via NMR spectroscopy and LC-MS analysis |
Primary Research Applications
2-FMA is supplied exclusively for established scientific frameworks, including:
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Monoamine Transporter Substrate Profiling: In-vitro mapping of the compound’s binding kinetics, efflux inhibition, and release induction profiles at the dopamine ($DAT$), norepinephrine ($NET$), and serotonin ($SERT$) transporter sites.
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Halogenation & Methylation Synergy: Investigating how the concurrent addition of an ortho-fluorine atom and an $N$-methyl group modifies the spatial and electronic configuration of the phenethylamine core structure.
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Metabolic Resistance Studies: Assessing the metabolic pathway degradation of fluorinated phenethylamines, with particular focus on how the highly stable $C\text{-}F$ bond alters standard aromatic hydroxylation kinetics.
Safety, Storage, and Regulatory Compliance
Strict adherence to standard laboratory safety protocols ($GLP$) is required during handling.
⚠️ Laboratory Notice & Intended Use
This compound is synthesized and distributed strictly for in-vitro laboratory research and analytical applications. It is explicitly not intended for human or veterinary diagnostic or therapeutic consumption.
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Documentation: All shipments are accompanied by a comprehensive Safety Data Sheet (SDS) detailing toxicological data, reactivity profiles, and safe handling procedures.
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Storage Conditions: To maintain chemical integrity and prevent degradation, store the compound in a cool, dark, and desiccated environment (ideally between $2^\circ\text{C}$ and $8^\circ\text{C}$ or below for long-term reference stability).
Institutional Procurement & Logistics
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Inventory Selection: Available in scalable quantities calibrated for varied institutional budget allocations and project scopes.
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Secure Transactions: Encrypted checkout protocols ensure the absolute protection of institutional procurement and proprietary data.
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Logistics: Shipped in secure, stable packaging to preserve chemical integrity during transit, complete with tracking and automated delivery confirmation... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Support and Technical Consultation
For volume inquiries, bulk pricing schedules, or to request batch-specific Certificates of Analysis (CoA), please submit a formal inquiry to our technical support desk via Chem S Supply.
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