2-METHYL-AP-237 HCl | Analytical Grade Cinnamylpiperazine for Research

Product Overview

2-FMA research amphetamine(2-Methyl-1-(4-(3-phenylprop-2-en-1-yl)piperazin-1-yl)butan-1-one hydrochloride) is a synthetic acylpiperazine derivative and a potent structural analog of AP-237 (Bucinnazine). According to the 2-METHYL-AP-237 HCl Wiki, this compound is characterized by a cinnamyl group attached to a piperazine core, featuring a distinct methyl substitution on the butyryl side chain. This specific structural alteration makes 2-METHYL-AP-237 HCl a primary subject of interest for investigators examining non-morphinan $\mu$-opioid receptor ligands, structure-activity relationships (SAR) of atypical analgesics, and monoamine modulation kinetics.

2-FMA research amphetamine

Researchers can source high-purity reagents and reference materials directly through Chem S Supply.

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Technical Specifications

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Primary Research Applications

2-METHYL-AP-237 HCl is supplied exclusively for established scientific frameworks, including:

• Opioid Receptor Binding Assays: In-vitro mapping of the compound’s binding affinity, selectivity, and intrinsic efficacy at the mu ($\mu$), delta ($\delta$), and kappa ($\kappa$) opioid receptor subtypes.

• Atypical Core SAR Studies: Investigating how methyl configurations on the acyl side chain of piperazine rings alter spatial orientation, molecular docking performance, and binding pocket interactions compared to classical morphinan or fentanyl-type templates.

• Metabolic and Toxicological Profiling: Mapping the enzymatic degradation pathways, clearance rates, and metabolite profiles of novel cinnamylpiperazines in hepatic models.

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Safety, Storage, and Regulatory Compliance

Strict adherence to standard laboratory safety protocols ($GLP$) is required during handling.

⚠️ Laboratory Notice & Intended Use

This compound is synthesized and distributed strictly for in-vitro laboratory research and analytical applications. It is explicitly not intended for human or veterinary diagnostic or therapeutic consumption.

• Documentation: All shipments are accompanied by a comprehensive Safety Data Sheet (SDS) detailing toxicological data, reactivity profiles, and safe handling procedures.

• Storage Conditions: To maintain chemical integrity and prevent degradation, store the compound in a cool, dark, and desiccated environment (ideally between 2∘C and 8∘C or below for long-term reference stability).

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Institutional Procurement & Logistics

• Inventory Selection: Available in scalable quantities calibrated for varied institutional budget allocations and project scopes.

• Secure Transactions: Encrypted checkout protocols ensure the absolute protection of institutional procurement and proprietary data.

• Logistics: Shipped in secure, stable packaging to preserve chemical integrity during transit, complete with tracking and automated delivery confirmation... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Support and Technical Consultation

For volume inquiries, bulk pricing schedules, or to request batch-specific Certificates of Analysis (CoA), please submit a formal inquiry to our technical support desk via Chem S Supply.