3-FEA | Analytical Grade Fluorinated Ethylamphetamine for Research

Product Overview

3-FA research amphetamine (3-Fluoroethamphetamine) is a synthetic ring-substituted fluorinated analog of ethylamphetamine and a prominent member of the phenethylamine class. According to the 3-FEA Wiki, its molecular structure features a fluorine atom substituted at the meta– ($3$-) position of the phenyl ring, combined with an $N$-ethyl modification on the amino group. This unique halogenated and alkylated configuration makes 3-FEA a primary subject of interest for investigators examining entactogenic vs. stimulant monoamine release profiles, structural-activity relationships (SAR), and transporter binding kinetics. It serves as a vital comparative reference standard alongside other fluorinated isomers like 2-FEA and 4-FEA... . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Researchers can source high-purity reagents and reference materials directly through Chem S Supply.

Technical Specifications

Primary Research Applications

3-FA research amphetamine is supplied exclusively for established scientific frameworks, including:

• Monoamine Transporter Selectivity Assays: In-vitro mapping of the compound’s dual mechanism as a substrate and reuptake inhibitor at the serotonin ($SERT$), dopamine ($DAT$), and norepinephrine ($NET$) transporters, specifically evaluating its enhanced serotonergic release ratio compared to non-ethylated variants.

• Structural-Activity Relationships (SAR): Investigating how the concurrent addition of an $N$-ethyl group and a meta-fluorine substitution alters the conformation of the phenethylamine backbone and affects its binding pockets.

• Metabolic & Degradation Tracking: Studying the hepatic enzyme pathways (such as cytochrome P450 mediated $N$-dealkylation) that metabolize 3-FEA into 3-FA and other subsequent metabolites.

Safety, Storage, and Regulatory Compliance

Strict adherence to standard laboratory safety protocols ($GLP$) is required during handling.

⚠️ Laboratory Notice & Intended Use

This compound is synthesized and distributed strictly for in-vitro laboratory research and analytical applications. It is explicitly not intended for human or veterinary diagnostic or therapeutic consumption.

• Documentation: All shipments are accompanied by a comprehensive Safety Data Sheet (SDS) detailing toxicological data, reactivity profiles, and safe handling procedures.

• Storage Conditions: To maintain chemical integrity and prevent degradation, store the compound in a cool, dark, and desiccated environment (ideally between $2^\circ\text{C}$ and $8^\circ\text{C}$ or below for long-term reference stability).

Institutional Procurement & Logistics

• Inventory Selection: Available in scalable quantities calibrated for varied institutional budget allocations and project scopes.

• Secure Transactions: Encrypted checkout protocols ensure the absolute protection of institutional procurement and proprietary data.

• Logistics: Shipped in secure, stable packaging to preserve chemical integrity during transit, complete with tracking and automated delivery confirmation.

Support and Technical Consultation

For volume inquiries, bulk pricing schedules, or to request batch-specific Certificates of Analysis (CoA), please submit a formal inquiry to our technical support desk via Chem S Supply.