Norflurazepam | Analytical Grade Benzodiazepine Reference Material

Product Overview

Norflurazepam research benzodiazepine (also known as $N$ -desalkylflurazepam) is a synthetic compound of the benzodiazepine class and a primary active metabolite of several established therapeutic agents, including flurazepam, midazolam, and quazepam. According to the Norflurazepam Wiki, its chemical structure is characterized by a 1,4-benzodiazepine core featuring a 2-fluorophenyl ring at the 5-position and a halogenated chlorine atom at the 7-position. Due to its exceptionally prolonged metabolic half-life and high binding affinity, Norflurazepam is a primary subject of interest for investigators examining $\text{GABA}_\text{A}$ receptor subtype modulation, forensic toxicology screening, and comparative metabolic clearance pathways.

Researchers can source high-purity reagents and reference materials directly through Chem S Supply.

Technical Specifications

Parameter	Specification
Chemical Name	7-chloro-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one
Class	1,4-Benzodiazepine
Concentration	Available as highly purified crystalline powder or analytical standard calibrated for quantitative verification
Format	Analytical grade powder optimized for chemical stability, precise mass measurement, and solution preparation
Purity	$\ge 98\%$ verified via NMR spectroscopy and LC-MS analysis

Primary Research Applications

Norflurazepam research benzodiazepine is supplied exclusively for established scientific frameworks, including:

$\text{GABA}_\text{A}$ Receptor Binding Kinetics: In-vitro mapping of the compound’s positive allosteric modulation at the benzodiazepine receptor site of the $\gamma$ -aminobutyric acid ( $\text{GABA}_\text{A}$ ) complex.
Forensic and Analytical Assay Development: Serving as a definitive reference standard for validating high-performance liquid chromatography ( $HPLC$ ) and gas chromatography-mass spectrometry ( $GC\text{-}MS$ ) detection matrices in toxicological screening.
Comparative Pharmacokinetic Modeling: Investigating the clearance rates, receptor site occupancy times, and metabolic stability of halogenated 1,4-benzodiazepines within cellular systems.

Safety, Storage, and Regulatory Compliance

Strict adherence to standard laboratory safety protocols ( $GLP$ ) is required during handling.

⚠️ Laboratory Notice & Intended Use

This compound is synthesized and distributed strictly for in-vitro laboratory research and analytical applications. It is explicitly not intended for human or veterinary diagnostic or therapeutic consumption.

Documentation: All shipments are accompanied by a comprehensive Safety Data Sheet (SDS) detailing toxicological data, reactivity profiles, and safe handling procedures.
Storage Conditions: To maintain chemical integrity and prevent thermal degradation, store the compound in a cool, dark, and desiccated environment (ideally between $2^\circ\text{C}$ and $8^\circ\text{C}$ or below for long-term reference stability).

Institutional Procurement & Logistics

Inventory Selection: Available in scalable quantities calibrated for varied institutional budget allocations and project scopes.
Secure Transactions: Encrypted checkout protocols ensure the absolute protection of institutional procurement and proprietary data.
Logistics: Shipped in secure, stable packaging to preserve chemical integrity during transit, complete with tracking and automated delivery confirmation.

Support and Technical Consultation

For volume inquiries, bulk pricing schedules, or to request batch-specific Certificates of Analysis (CoA), please submit a formal inquiry to our technical support desk via Chem S Supply.